Visual Legend

Filter Edges

Edge Type

Color

IN_SAME_COMPONENT  
Edge is drawn if the first entity is a component of the second entity, which is a complex. This interaction is transient in the sense that A COMPONENT_OF B and B COMPONENT_OF C implies A COMPONENT_OF C. This interaction is undirected.
COMPONENT_OF  
Edge is drawn if two entities belong to at least one molecular complex. This does not necessarily mean they interact directly. In a complex with n molecules, this rule will create a clique composed of n(n-1)/2 interactions. This interaction is directed.
CO_CONTROL_DEPENDENT_ANTI  
Edge is drawn if the first and second entities have control over the same process, their control is dependent, i.e. one of them have effect over control of the other one, and their effect is in different directions (one of them activates, the other inhibits. This interaction is undirected."
CO_CONTROL_DEPENDENT_SIMILAR  
Edge is drawn if the first and second entities have control over the same process, their control is dependent, i.e. one of them have effect over control of the other one, and their effect is in the same direction (both activates or both inhibits). This interaction is undirected.
CO_CONTROL_INDEPENDENT_ANTI  
Edge is drawn if the first and second entities have control over the same process, their control is independent, i.e. they act without affecting each other's activity, and their effect is in different directions (one of them activates, the other inhibits. This interaction is undirected.
CO_CONTROL_INDEPENDENT_SIMILAR  
Edge is drawn if the first and second entities have control over the same process, their control is independent, i.e. they act without affecting each other's activity, and their effect is in the same direction (both activates or both inhibits). This interaction is undirected.
METABOLIC_CATALYSIS  
Edge is drawn if the first entity catalyses a reaction that either consumes or produces the second entity. More specifically, this rule will find an interaction between two entities A and B if and only if A controls a conversion which B participates and appears only on the left or right side of the conversion but not both. This interaction is directed.
STATE_CHANGE  
Edge is drawn if the first entity catalyses a reaction that either consumes or produces the second entity. More specifically, this rule will find an interaction between two entities A and B if and only if A controls a conversion which B participates and appears both on the left or right side of the conversion. This interaction is directed.
REACTS_WITH  
Edge is drawn if both A and B participates in a conversion as substrates or products. Controllers are not included. This interaction is undirected.
INTERACTS_WITH  
Edge is drawn if both A and B participates in an interaction as participants. Controllers are not included. This interaction is undirected.
SEQUENTIAL_CATALYSIS  
Edge is drawn if A and B catalyzes two conversions that are connected via a common molecule, and where potentially that common substrate is produced by the former and consumed by the latter. This interaction is directed.