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CAP 5510: Introduction to Bioinformatics
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Lecture: MW 1:30PM - 2:45PM
Location: BA 209
Instructor: Dr.
Haiyan Nancy Hu
Email: haihu@cs.ucf.edu
Office: HEC- 233
Phone Number: 407-882-0134
Office Hours: MW 10:00AM - 11:00AM
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Description:
This course will introduce students to the rapidly developing bioinformatics field, and will train graduate students so that they are aware of current research problems in bioinformatics and they are prepared to develop more advanced methods and tools for bioinformatics applications.
Bioinformatics is an active and interdisciplinary research area. This course is open to all students with background such as computer science, biology, mathematics or statistics who are interested in bioinformatics research.
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Prerequisite:
No formal prerequisite and open to all graduate students.
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Book Reference:
Durbin, Eddy, Krogh, Mitchison "Biological Sequence Analysis"
Gusfield "Algorithms on Strings, Trees, and Sequences"
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Grading:
Assignments (30%), Midterm (20%) and Final project (50%).
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Preliminary
Schedule:
| Date |
Topic |
Notes and References* |
| W1: 08/22 |
Introduction/Administrivia |
Notes |
| 08/24 |
DNA the genome |
Notes |
| W2: 08/29 |
Sequence alignment and dynamic programming |
Notes |
| 08/31 |
Sequence alignment and BLAST |
Notes, |
| W3: 09/05 |
Labor day, no class |
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| 09/07 |
Sequence alignment and Hidden Markov Model |
Notes |
| W4: 09/12 |
Sequence alignment and Hidden Markov Model |
Notes, |
| 09/14 |
Sequence alignment and Hidden Markov Model |
Notes, |
| W5: 09/19 |
Conditonal Random Fields |
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| 09/21 |
Context Free Grammars |
Notes |
| W6: 09/26 |
Gene Regulation |
Notes, |
| 09/28 |
motif finding |
Notes; |
| W7: 10/03 |
motif finding |
Notes, |
| 10/05 |
motif finding |
Notes, |
| W8: 10/10 |
motif finding |
Notes, |
| 10/12 |
motif finding |
Notes, |
| W9: 10/17 |
midterm |
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| 10/19 |
mRNA gene expression |
Notes, |
| W10: 10/24 |
functional element prediction |
Notes, |
| 10/26 |
gene expression data analysis |
Notes |
| W11: 10/31 |
clustering Biclustering |
Notes; |
| 11/02 |
Cancer classification using gene expression data |
Notes; |
| W12: 11/07 |
Gene ontology and function annotation |
Notes;
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| 11/9 |
Gene ontology and function annotation |
Notes,
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| W13: 11/14 |
Most current topics |
Notes; |
| 11/16 |
Most current topics |
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| W14: 11/21 |
Most current topics |
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| 11/23 |
Most current topics |
| W15: 11/28 |
Most current topics |
| 11/30 |
Most current topics |
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